cysteines disulfide bonding state and connectivity predictor
'disulfinder' is for predicting the disulfide bonding state of cysteines
and their disulfide connectivity starting from sequence alone. Disulfide
bridges play a major role in the stabilization of the folding process for
several proteins. Prediction of disulfide bridges from sequence alone is
therefore useful for the study of structural and functional properties
of specific proteins. In addition, knowledge about the disulfide bonding
state of cysteines may help the experimental structure determination
process and may be useful in other genomic annotation tasks.
'disulfinder' predicts disulfide patterns in two computational stages:
(1) the disulfide bonding state of each cysteine is predicted by a
BRNN-SVM binary classifier; (2) cysteines that are known to participate
in the formation of bridges are paired by a Recursive Neural Network
to obtain a connectivity pattern.
* A. Ceroni, A. Passerini, A. Vullo and P. Frasconi. DISULFIND: a
Disulfide Bonding State and Cysteine Connectivity Prediction Server,
Nucleic Acids Research, 34(Web Server issue):W177-W181, 2006.
For the disulphide connectivity predictor see:
* A. Vullo and P. Frasconi. Disulfide Connectivity Prediction using
Recursive Neural Networks and Evo
DISULFINDER(1) User Commands DISULFINDER(1)
disulfinder - cysteines disulfide bonding state and
'disulfinder' is for predicting the disulfide bonding state
of cysteines and their disulfide connectivity starting from
sequence alone. Disulfide bridges play a
disulfinder (1.2.11-2+b1) sid; urgency=low
* Binary-only non-maintainer upload for i386; no source changes.
* Rebuild against boost1.49
-- i386 Build Daemon <firstname.lastname@example.org> Sat, 07 Apr 2012 08:58:54 +0000
disulfinder (1.2.11-2) unstable; urgency=low
* added mkdir debian/disulfinder-data/usr/share/disulfinder/ to
debian/rules before moving Models to disulfinder
disulfinder (1.2.11) unstable; urgency=low
* examples now installed into $(docdir)/examples
This package was debianized by Laszlo Kajan <email@example.com> on
Fri, 30 Oct 2009 12:12:21 +0100.
Browse inside disulfinder_1.2.11-2+b1_i386.deb
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